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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KSR2 All Species: 5.76
Human Site: T188 Identified Species: 12.67
UniProt: Q6VAB6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6VAB6 NP_775869.3 950 107632 T188 P V C P P E P T P W I R T H L
Chimpanzee Pan troglodytes XP_001145739 986 111275 T164 P V C P P E P T P W I R T H L
Rhesus Macaque Macaca mulatta XP_001083311 805 90894 H112 P P S P R Q R H A V R T P P R
Dog Lupus familis XP_853953 898 99758 G182 G E H K E D S G W S S L D A R
Cat Felis silvestris
Mouse Mus musculus Q3UVC0 959 108554 P189 V C P P E P S P W I R T H L S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514916 259 29171
Chicken Gallus gallus Q04982 806 89347 S113 G T D F S V S S S A S T D T V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001137513 942 106704 H186 T P V G P S D H S Q W V R L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P11346 782 88616 I89 P T Y V Y V C I S R L W F L P
Honey Bee Apis mellifera XP_393005 895 100160 S162 D M N L Y W D S W D R H H L R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q05609 821 90288 Q128 I E S V G F P Q D D G F R L G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.1 84.3 51 N.A. 95.5 N.A. N.A. 25.1 24.3 N.A. 82.3 N.A. 24.9 36.4 N.A. N.A.
Protein Similarity: 100 92.1 84.5 64.6 N.A. 97 N.A. N.A. 26.3 40.2 N.A. 90.1 N.A. 40.9 53.5 N.A. N.A.
P-Site Identity: 100 100 13.3 0 N.A. 6.6 N.A. N.A. 0 0 N.A. 6.6 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 100 20 6.6 N.A. 6.6 N.A. N.A. 0 13.3 N.A. 6.6 N.A. 13.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 10 0 0 0 10 0 % A
% Cys: 0 10 19 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 10 19 0 10 19 0 0 19 0 0 % D
% Glu: 0 19 0 0 19 19 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 10 0 0 0 0 0 10 10 0 0 % F
% Gly: 19 0 0 10 10 0 0 10 0 0 10 0 0 0 10 % G
% His: 0 0 10 0 0 0 0 19 0 0 0 10 19 19 0 % H
% Ile: 10 0 0 0 0 0 0 10 0 10 19 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 10 10 0 46 19 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 37 19 10 37 28 10 28 10 19 0 0 0 10 10 10 % P
% Gln: 0 0 0 0 0 10 0 10 0 10 0 0 0 0 10 % Q
% Arg: 0 0 0 0 10 0 10 0 0 10 28 19 19 0 28 % R
% Ser: 0 0 19 0 10 10 28 19 28 10 19 0 0 0 10 % S
% Thr: 10 19 0 0 0 0 0 19 0 0 0 28 19 10 0 % T
% Val: 10 19 10 19 0 19 0 0 0 10 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 10 0 0 28 19 10 10 0 0 0 % W
% Tyr: 0 0 10 0 19 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _